Journal: Journal of Ginseng Research

Article Title: Protective effect of ginsenosides Rk3 and Rh4 on cisplatin-induced acute kidney injury in vitro and in vivo

doi: 10.1016/j.jgr.2016.03.008

Figure Lengend Snippet: Effects of ginsenoside Rk3 and Rh4 (KG-KH) on body weight, kidney weight, kidney index, blood urea nitrogen (BUN), and creatinine in cisplatin-injected rats

Article Snippet: Diagnostic kits for measurement of blood urea nitrogen (BUN) and creatinine were purchased from Asan Pharmaceuticals (Seoul, Korea).

Techniques:

Journal: Frontiers in Medicine

Article Title: Oxypurinol protects renal ischemia/reperfusion injury via heme oxygenase-1 induction

doi: 10.3389/fmed.2023.1030577

Figure Lengend Snippet: Oxypurinol protects against renal ischemia/reperfusion injury via heme oxygenase-1 (HO-1) induction. C57BL/6 male mice were subjected to sham or 30 min of renal ischemia surgeries. Some mice were pretreated with 25 or 50 mg/kg of oxypurinol at 24 h and 1 h preoperatively. To test whether HO-1 induction is critical for oxypurinol-mediated renal protection against renal I/R injury, we injected an HO-1 inhibitor [25 mg/kg, tin protoporphyrin IX (SnPP)] before oxypurinol first treatment. Some mice were pretreated with 25 mg/kg of hemin at 24 hours preoperatively. (A, B) Twenty-four hours after surgeries, plasma creatinine (PCr) and blood urea nitrogen (BUN) levels were measured. (C) Kidney samples were subjected to Western blotting using an anti-HO-1 antibody. GAPDH was used as a loading control. (D) Band intensities were measured using ImageJ. (E) Representative images (magnification, 200×) of kidney sections subjected to hematoxylin and eosin (H&E) are shown. (F) Histological damages were analyzed as described in the Materials and Methods section. Results are expressed as means ± standard errors of the mean (SEM) (vehicle or oxypurinol [oxy] sham n = 4; vehicle, oxypurinol, SnPP, or SnPP + oxypurinol renal ischemia/reperfusion (RIR) n = 6). * P < 0.05 vs. vehicle sham; † P < 0.05 vs. vehicle RIR; # P < 0.05 vs. oxypurinol RIR.

Article Snippet: Twenty-four hours after surgery, we measured plasma creatinine (PCr) and blood urea nitrogen (BUN) levels using creatinine and urea nitrogen reagent kits (BioAssay Systems, Hayward, CA).

Techniques: Injection, Clinical Proteomics, Western Blot, Control

Journal: Heliyon

Article Title: Up-regulation of PKR pathway contributes to L-NAME induced hypertension and renal damage

doi: 10.1016/j.heliyon.2020.e05463

Figure Lengend Snippet: Estimation of Serum creatinine and blood urea nitrogen (BUN): Statistical analysis was carried out by applying one-way ANOVA, Bonferroni test was used for post hoc analysis.

Article Snippet: Commercial kits for assessment of serum creatinine, blood urea nitrogen, (BUN) were purchased from Arkray Health care Pvt.

Techniques: